Therapeutic Endoscopy: Advanced Techniques for Minimally Invasive GI Interventions
Therapeutic endoscopy offers minimally invasive alternatives to traditional surgery for GI disorders, featuring advanced techniques like ERCP and EUS-guided interventions. These procedures provide faster recovery times, shorter hospital stays, and lower complication rates while effectively treating complex digestive conditions.
Revolutionary Approach
Transforming digestive disorder treatments through sophisticated endoscopic approaches including ERCP, EUS-guided interventions, and third space endoscopy. These techniques allow gastroenterologists to perform complex procedures like endoscopic mucosal resection, bile duct stenting, and pancreatic pseudocyst drainage without conventional surgery.
60%
Faster Recovery
Quicker patient recovery compared to traditional surgical interventions
40%
Reduced Hospitalization
Shorter hospital stays for patients undergoing therapeutic endoscopy
Therapeutic endoscopy continues to revolutionize GI care with significantly lower complication rates compared to traditional surgical interventions.
Shaheen Rasheed, M.D.
Breaking Boundaries in Gastroenterology: Dr. Rasheed's Minimally Invasive Vision
Interventional Gastroenterologist
Distinguished specialist in pioneering endoscopic procedures including complex ERCP, advanced endoscopic ultrasound, and ERCP in challenging altered anatomy (Roux-en-Y) cases. Recognized expert in sophisticated interventional techniques such as precision-guided nerve blocks for pancreatic cancer pain management and minimally invasive pancreatic cyst drainage. Tailored Endoscopic Therapies: Expert in E-POEM, G-POEM, and Z-POEM for Precise Digestive Disorder Management Providing personalized endoscopic solutions for specific digestive disorders to enhance patient outcomes.
Board Certified
Leading Innovation in Gastroenterology: Board-Certified Specialist with Advanced Endoscopy Expertise Committed to setting new standards of care by staying at the forefront of emerging techniques in therapeutic endoscopy..
Mastering the Art of Care
For over 15 years, Dr. Rasheed has combined technical precision with empathetic communication to ensure patients receive superior medical treatment and comprehensive support throughout their care journey.
Understanding Therapeutic Endoscopy Fundamentals
Therapeutic endoscopy combines diagnosis and treatment using specialized equipment and high-definition imaging. Patient preparation is crucial for successful outcomes.
Beyond Diagnostics
Unlike diagnostic procedures, therapeutic endoscopy actively treats conditions during examination. This dual-purpose approach uses specialized flexible, rigid, and custom endoscopes designed for specific interventions.
High-definition imaging and narrow-band visualization technologies allow physicians to perform complex procedures with remarkable precision in specially equipped environments.
Proper patient preparation is essential for successful outcomes, with protocols varying based on the target area and specific intervention planned.
Advanced Endoscopic Resection Techniques
Specialized techniques for removing precancerous lesions and early cancers without surgery, using various approaches to extract tissue specimens for pathological evaluation.
Endoscopic Mucosal Resection (EMR) allows precise removal of suspicious lesions confined to the mucosa without invasive surgery.
1
Precision Targeting
Removes precancerous lesions and early-stage cancers up to 2cm with submucosal injection.
2
Technique Variations
Includes cap-assisted, ligation-assisted, and underwater EMR approaches for different anatomical challenges.
3
Histological Assessment
Provides intact tissue specimens for complete pathological evaluation of margins and invasion depth.
Endoscopic Submucosal Dissection (ESD)
A precision technique for en bloc removal of larger lesions, preserving organ function while achieving complete resection with clear margins.
Specialized Tools
Utilizes dedicated knives and equipment for meticulous dissection beneath the mucosa.
Complete Excision
Enables en bloc removal of lesions >2cm with intact margins for thorough pathological assessment.
Technical Expertise
Requires advanced endoscopic skill and specialized training to minimize complications.
Endoscopic Full Thickness Resection
A specialized technique for complete wall-layer removal of non-lifting and subepithelial lesions using an integrated clip-and-cut device, providing thorough pathological assessment while avoiding surgery.
This technique enables complete removal of GI lesions involving all digestive tract wall layers, with 45-90 minute procedure times and >90% success rates for suitable lesions.
Target Lesions
Targets non-lifting lesions, recurrent adenomas, and subepithelial tumors (≤30mm) in the colon, rectum, and stomach.
One-Step Procedure
Utilizes FTRD® device with integrated clip system and snare that secures closure before resection, minimizing perforation risk.
Complete Pathology
Provides en bloc specimens (15-30mm) with all wall layers intact for definitive diagnosis of invasion depth and accurate T-staging.
Organ Preservation
Reduces surgical need in 80% of cases, with minimal complications (3-5% bleeding, 2% pain) and shorter hospital stays (24-48 hours vs. 5-7 days for surgery).
Pancreaticobiliary Therapeutic Endoscopy
Advanced endoscopic techniques for treating bile duct and pancreatic disorders through minimally invasive procedures including ERCP, stenting, and ultrasound-guided interventions.
ERCP Procedures
Specialized endoscopic technique providing access to the bile and pancreatic ducts for diagnosis and treatment of various conditions including stone removal, stricture dilation, and tissue sampling.
Biliary and Pancreatic Stenting
Placement of temporary or permanent stents to maintain patency of obstructed ducts, allowing proper drainage and preventing complications.
EUS-Guided Interventions
Ultrasound-guided techniques for precise fine needle aspiration, pseudocyst drainage, and targeted therapy delivery to previously inaccessible areas.
Endoscopic Retrograde Cholangiopancreatogram (ERCP)
A specialized therapeutic procedure combining endoscopy and fluoroscopy to visualize and treat disorders of the pancreaticobiliary system.
Endoscope Placement
Side-viewing duodenoscope positioned at papilla of Vater in duodenum.
Duct Cannulation
Contrast medium injected into biliary or pancreatic ducts.
Fluoroscopic Imaging
Real-time X-ray visualization of ductal anatomy and pathology.
Therapeutic Intervention
Sphincterotomy, stone extraction, stent placement, or tissue sampling performed.
ERCP Cholangioscopy
Direct visualization technique allowing real-time examination and treatment of bile ducts during ERCP procedures.
Advanced endoscopic technology providing high-definition imaging of the biliary system for targeted therapy, precise biopsies, and improved success rates in complex cases.
Enhanced Visualization
High-definition imaging of biliary tree provides detailed views of strictures, stones, and lesions.
2
Targeted Therapy
Enables direct fragmentation of difficult stones using electrohydraulic or laser lithotripsy.
3
Optical Biopsy
Facilitates precise tissue sampling of suspicious lesions under direct visualization.
Improved Outcomes
Reduces need for repeated procedures with 90% success rate for complex cases.
Bile Duct and Pancreatic Stenting
Advanced endoscopic techniques to restore proper drainage in obstructed ductal systems.
Endoscopic stenting procedures involve careful assessment, appropriate stent selection, precise placement techniques, and thorough post-procedure monitoring to effectively treat biliary and pancreatic obstructions.
Pre-Stenting Assessment
Detailed imaging studies identify exact location and nature of the obstruction.
Stent Selection
Material, diameter, and length chosen based on stricture characteristics and expected duration.
Placement Technique
Guidewire navigation through the stricture followed by precise deployment under fluoroscopic guidance.
Post-Procedure Monitoring
Clinical improvement tracked through symptom relief, laboratory values, and follow-up imaging.
Endoscopic Ultrasound-Guided Interventions
Advanced minimally invasive techniques combining ultrasound imaging with therapeutic procedures for precise diagnosis and treatment.
1
Fine Needle Aspiration/Biopsy
Real-time ultrasound visualization enables precise sampling of lesions with minimal tissue disruption.
Fluid Collection Drainage
Direct access to pancreatic pseudocysts and walled-off necrosis through transgastric or transduodenal approaches.
3
Celiac Plexus Neurolysis
Targeted injection of neurolytic agents for pain management in pancreatic cancer patients.
4
Biliary Access
Alternative route for failed ERCP cases through hepaticogastrostomy or choledochoduodenostomy techniques.
Endoscopic Ultrasound-Guided Gastrojejunostomy
Minimally invasive alternative to surgery for gastric outlet obstruction, offering fewer complications and reduced risks.
Planning the Procedure
Ultrasound imaging identifies optimal stomach-intestine connection point. Small intestine is distended with fluid for better visualization.
Creating Access
Specialized needle traverses stomach wall under fluoroscopic guidance. Contrast injection confirms position before guidewire placement.
Placing the Stent
Metal stent deployment creates permanent gastrojejunal bypass. Position verification through endoscopy and fluoroscopy, with possible dilation for optimal patency.
Patient Benefits
95% technical success with 87% long-term efficacy. 35-minute procedure reduces hospitalization from 11 to 3 days, enabling faster oral intake and recovery.
Endoscopic Treatment for Pancreatic Necrosis
Minimally invasive approach for managing infected or symptomatic pancreatic necrosis, significantly reducing morbidity compared to surgical interventions.
Endoscopic necrosectomy offers a staged, minimally invasive approach to manage pancreatic necrosis through careful assessment, transmural access, direct debridement, and ongoing monitoring, resulting in reduced patient morbidity.
Walled-Off Assessment
EUS evaluation confirms mature encapsulation and optimal access route through gastric or duodenal wall.
Transmural Access Creation
Large-diameter metal stent placement creates sustained drainage pathway into necrotic collection.
Direct Necrosectomy
Endoscope advanced through stent with specialized tools to remove necrotic debris in multiple sessions.
Lavage and Follow-Up
Saline irrigation clears residual material. Sequential imaging confirms resolution of collection.
Third Space Endoscopy
Revolutionary techniques accessing the submucosal space for advanced interventions without external incisions.
1
Submucosal Tunneling
Creating access pathways between tissue layers for minimally invasive interventions.
POEM Procedure
Per-Oral Endoscopic Myotomy treats achalasia by targeting esophageal muscle fibers.
3
G-POEM
Gastric peroral endoscopic myotomy addresses gastroparesis through pyloric muscle division.
4
STER
Submucosal Tunneling Endoscopic Resection removes subepithelial tumors with intact overlying mucosa.
Luminal Stenting
Restoring patency in obstructed gastrointestinal segments through targeted stent placement.
1
Stricture Assessment
Location, length, and cause determine appropriate stent selection.
Stent Selection
Self-expanding metal, and plastics based on clinical scenario.
3
Precise Deployment
Fluoroscopic guidance ensures optimal positioning across strictures.
4
Follow-Up Protocol
Scheduled assessment for migration, obstruction, or tissue overgrowth.
Endoscopic Suturing
Sophisticated endoluminal technique enabling precise tissue approximation and complex defect closure entirely within the gastrointestinal tract lumen.
Endoscopic suturing represents a paradigm shift in interventional endoscopy, offering minimally invasive solutions for GI tract repairs, bariatric procedure revisions, refractory hemorrhage control, and stent stabilization—eliminating the need for conventional surgical intervention.
Defect Closure
Hermetic closure of iatrogenic perforations, persistent fistulae, and postoperative anastomotic leaks with significantly reduced patient morbidity compared to surgical repair.
Bariatric Applications
Endoluminal revision of dilated gastrojejunal anastomoses, management of weight recidivism, and remediation of sleeve gastrectomy complications including reflux and leakage.
Hemostasis
Definitive management of complex bleeding diatheses and vascular lesions refractory to conventional hemostatic techniques, including Dieulafoy's lesions and post-polypectomy hemorrhage.
Stent Fixation
Prevents migration and associated complications by anchoring self-expanding metal stents securely to adjacent tissue, dramatically improving technical and clinical success rates in palliative interventions.
Barrett's Cryoablation
A tissue-sparing freezing technique used to treat Barrett's esophagus by destroying precancerous cells while minimizing damage to surrounding healthy tissue structure.
Advanced endoscopic therapy utilizing extreme cold to eliminate precancerous tissue in Barrett's esophagus while preserving underlying structural integrity.
Cryogen Delivery
Liquid nitrogen or carbon dioxide spray applied directly to dysplastic tissue.
Cellular Destruction
Rapid freezing induces crystallization within abnormal cells, causing apoptosis.
Structural Preservation
Maintains esophageal architecture with minimal stricture formation compared to thermal methods.
Treatment Protocol
Typically requires 2-4 sessions at 8-week intervals for complete eradication.
Endoscopic Treatment for Esophageal Cancer
Advanced endoscopic techniques offer curative treatment for early esophageal cancers through a systematic approach of detection, resection, ablation, and surveillance—providing alternatives to major surgery.
Minimally invasive endoscopic approaches offering curative options for early-stage esophageal neoplasia with significantly reduced morbidity compared to traditional esophagectomy.
Early Detection
High-definition endoscopy with narrow-band imaging identifies subtle mucosal abnormalities in early-stage disease.
Endoscopic Resection
EMR and ESD techniques remove focal lesions confined to mucosa with clear margins.
Ablative Therapy
Radiofrequency ablation eliminates residual Barrett's epithelium after resection of visible lesions.
Surveillance Protocol
Rigorous follow-up endoscopy at 3-month intervals initially, then extending to annual examinations.
Endoscopic Fistula Closure
Minimally invasive technique for sealing abnormal connections between organs or vessels, offering reduced morbidity compared to traditional surgical approaches.
1
Fistula Identification
Precise localization using endoscopic visualization and contrast studies.
2
Tissue Preparation
Debridement and freshening of fistula margins to promote healing.
3
Closure Technique
Application of clips, stents, sutures to obliterate fistula tract.
4
Follow-up
Serial imaging to confirm successful closure and monitor for recurrence.
Endoscopic Vacuum Therapy
A specialized endoscopic technique using negative pressure through a sponge system to manage and heal complex GI perforations and leaks.
Overview
A cutting-edge technique for managing complex gastrointestinal leaks and perforations, offering a minimally invasive alternative to traditional surgical interventions.
Therapeutic Procedure
Placement
Endoscopically positioned polyurethane sponge with suction tubing at the defect site.
Negative Pressure
Continuous suction promotes granulation and accelerates wound healing.
Drainage
Effectively removes secretions and debris, reducing infection risk.
Closure
Gradual approximation of wound edges, facilitating defect closure over time.
Management of Complications in Therapeutic Endoscopy
Effective management of therapeutic endoscopy complications relies on prompt recognition and targeted interventions for bleeding, perforation, infection, and sedation-related events, with outcomes directly correlated to the speed and appropriateness of the response.
Bleeding Control
Implementation of multi-modal hemostasis including 1:10,000 epinephrine injection, targeted bipolar or argon plasma coagulation at 40W, and deployment of through-the-scope hemoclips or over-the-scope clips for vessels >2mm.
Hemostatic powders and topical thrombin provide adjunctive control for diffuse bleeding surfaces.
Perforation Management
Immediate defect closure within 4-6 hours using endoscopic techniques including TTSC clips for defects <10mm, over-the-scope clips for 10-30mm defects, and endoscopic suturing for larger perforations.
Temporary fully-covered stents may be deployed for esophageal or duodenal perforations with radiographic confirmation and monitoring.
Team Preparedness
Comprehensive training in complication management techniques and regular simulation drills ensure endoscopy teams maintain readiness for adverse events.
All units should maintain a complications registry with regular morbidity reviews to identify improvement opportunities.
Future Directions in Therapeutic Endoscopy
Artificial Intelligence
Machine learning algorithms enhance lesion detection, characterization, and guide real-time procedure decisions with superhuman precision. AI systems continually improve through analysis of procedural databases.
Robotic Endoscopy
Robotic platforms enhance stability, precision, and ergonomics while enabling remote procedures. Specialized attachments allow for complex maneuvers beyond human dexterity limitations.
Novel Devices
Next-generation tissue approximation tools, resection devices, and closure systems streamline procedures while improving outcomes. Biodegradable stents and smart materials respond to physiological changes.